Sfoglia per Autore SALVATORELLI, EMANUELA
Doxorubicin metabolism to toxic species in human myocardium: stimulation by paclitaxel and docetaxel but not BMS 184476 or BMS 188797
2000-01-01 Minotti, G; Giancristofaro, G; Menna, P; Salvatorelli, E; Licata, S; Gianni, L
Taxanes stimolate Doxorubicin conversion to its cardiotoxic secondary alcohol metabolite doxorubicinol: studies in human myocardium
2001-01-01 Minotti, G.; Giancristofaro, G.; Menna, P.; Salvatorelli, E; Licata, S.; Saponiero, A.; Gianni, L.
Doxorubicin dependent reduction of hypervalent ferrylmyoglobin: One more evidence against the oxidative nature of doxorubicin-induced cardiotoxicity
2001-01-01 Menna, P.; Salvatorelli, E.; Liberati, G.; Giampietro, R.; Toppi, E.; Minotti, G
Taxanes stimulate doxorubicin conversion to its cardiotoxic secondary alcohol metabolite : Studies in human myocardium.
2001-01-01 Minotti, G; Giancristofaro, G.; Menna, P.; Salvatorelli, E.; Licata, S.; Saponiero, A.; Gianni, L.
Doxorubicin irreversibly inactivates iron regulatory protein-1 and –2 in cardiomyocytes: evidence for distinct metabolic pathways and implication for iron-mediated cardiotoxicity of antitumor therapy
2001-01-01 Minotti, G; Ronchi, R; Salvatorelli, E; Menna, P; Cairo, G
Doxorubicin irreversibly inactivates Iron Regulatory Proteins 1 and 2 in cardiomyocytes : Evidence for distinct metabolic pathways and implications for iron-mediated cardiotoxicity of antitumor therapy
2001-01-01 Minotti, G.; Ronchi, R.; Salvatorelli, E.; Menna, P; A, ; Cairo, G.
Impairment of myocardial contractility by anticancer anthracyclines: role of secondary alcohol metabolites and evidence of reduced toxicity by a novel disaccharide analogue
2001-01-01 Minotti, G; Parlani, M; Salvatorelli, E; Menna, P; Cipollone, A; Animati, F; Maggi, Ca; Manzini, S
Doxorubicin-Dependent Reduction of Ferrylmyoglobin and Inhibition of Lipid Peroxidation: Implications for Cardiotoxicity of Anticancer Anthracyclines
2002-01-01 Menna, P.; Salvatorelli, E.; Giampietro, R.; Liberi, G.; Teodori, G.; Calafiore, A. M.; Minotti, G
The novel anthracycline MEN 10755 is less cardiotoxic than doxorubicin or epirubicin due to reduced formation and aconitase-reactivity its secondary alcohol metabolite
2003-01-01 Menna, P; Salvatorelli, Emanuela; R., Giampietro; N., Bertani; G., Graiani; F., Animati; C., Goso; C. A., Maggi; S., Mancini; G., Sacco; Minotti, G.
Ferrylmyoglobin-dependent oxidative degradation of doxorubicin: a novel pathway of anthracycline metabolism and toxicity
2003-01-01 Menna, P.; Salvatorelli, E.; Braghiroli, D.; Giampietro, R.; Cartoni, A.; Animati, F.; Minotti, G
Doxorubicin inhibits ferrylmyoglobin-dependent lipid peroxidation
2003-01-01 Minotti, G; Menna, P; Salvatorelli, E; Giampietro, R
Chronic cardiotoxicity of anticancer anthracyclines in the rat: role of secondary metabolites and reduced toxicity by a novel anthracycline with impaired metabolite formation and reactivity
2003-01-01 Sacco, G.; Giampietro, R.; Salvatorelli, E.; Menna, P; Bertani, N.; Graiani, G.; Animati, F.; Goso, C.; Maggi, C. A.; Mancinis, S.; Minotti, G.
Formation of toxic anthracycline secondary alcohol metabolites in human myocardium: Comparisons between doxorubicin and epirubicin and effects of paclitaxel, docetaxel, and the epothilones BMS310705 and BMS247550
2004-01-01 Salvatorelli, E.; Gianni, L.; Marsoni, S.; Minotti, G
Doxorubicin Cardiotoxicity and the Control of Iron Metabolism: Quinone-Dependent and Independent Mechanisms
2004-01-01 Minotti, G.; Recalcati, S.; Menna, P.; Salvatorelli, E.; Corna, G.; Cairo, G.
Oxidative degradation of cardiotoxic anticancer anthracyclines to phthalic acids. Novel function or ferrylmyoglobin
2004-01-01 Cartoni, Antonella; Menna, Pierantonio; Salvatorelli, Emanuela; Braghiroli, Daniela; Giampietro, Rossella; Animati, Fabio; Urbani, Andrea; Del Boccio, Piero; Minotti, Giorgio
Phase IB and pharmacological study of the novel taxane BMS-184476 in combination with doxorubicin
2004-01-01 Sessa, C; Perotti, A; Salvatorelli, E; Minotti, G; Vigano, L; Llado, A; Capri, G; Locatelli, A; Colombini, S; Peccatori, F; Voi, M; Marsoni, S; Gianni, L.
Anthracyclines: molecular advances and pharmacological developments in antitumor activity and cardiotoxicity
2004-01-01 Minotti, G; Menna, P; Salvatorelli, E; Cairo, G; Gianni, L.
Role of secondary alcohol metabolites in anthracycline cardiotoxicity: from hypotheses to new drugs
2005-01-01 Salvatorelli, E.; Minotti, G.; Menna, P.
Molecular determinants of the reduced cardiotoxicity of epirubicin
2005-01-01 Salvatorelli, E.; Guarnieri, S.; Menna, P; Cascegna, S.; Minotti, G.
Defective one or two electron reduction of the anticancer anthracycline epirubicin in human heart: Relative importance of vesicular sequestration and impaired efficiency of electron addition
2006-01-01 Salvatorelli, E; Guarnieri, S; Menna, P; Liberi, G; Calafiore, Am; Mariggio, Ma; Mordente, A; Gianni, L; Minotti, G
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