Sfoglia per Autore MENNA, PIERANTONIO
MEN 10755 : A novel disaccharide anthracycline with a reduced level of formation and [4Fe-4S]-reactivity of toxic alcohol metabolite in human heart .
1999-01-01 Minotti, G; Licata, S.; Saponiero, A.; Menna, P.; Animati, F.; Cipollone, A.; Manzini, S.; Maggi, C. A.
Anthracycline metabolism and toxicity in human myocardyum: Comparisons between doxorubicin, epirubicin, and a novel disaccaride analogue with redeced formation and [4Fe-4S]-reactivity of its secondary alchol metabolite
2000-01-01 Minotti, G.; Licata, S.; Saponiero, A.; Menna, P; Calafiore, A. M.; Di Giammarco, G.; Liberi, G.; Animati, F.; Cipollone, A.; Mancini, S.; Maggi, C. A.
Doxorubicin metabolism to toxic species in human myocardium: stimulation by paclitaxel and docetaxel but not BMS 184476 or BMS 188797
2000-01-01 Minotti, G; Giancristofaro, G; Menna, P; Salvatorelli, E; Licata, S; Gianni, L
Taxanes stimolate Doxorubicin conversion to its cardiotoxic secondary alcohol metabolite doxorubicinol: studies in human myocardium
2001-01-01 Minotti, G.; Giancristofaro, G.; Menna, P.; Salvatorelli, E; Licata, S.; Saponiero, A.; Gianni, L.
MEN 10755: a novel disaccaride anthracycline with a reduced level of formation and [4Fe-4S]- reactivity of toxic alcohol metabolite in human myocardium
2001-01-01 Minotti, G.; Licata, S.; Saponiero, A.; Menna, P; Animati, F.; Cipolline, A.; Maggi, S. Manzini and C. A.
Doxorubicin dependent reduction of hypervalent ferrylmyoglobin: One more evidence against the oxidative nature of doxorubicin-induced cardiotoxicity
2001-01-01 Menna, P.; Salvatorelli, E.; Liberati, G.; Giampietro, R.; Toppi, E.; Minotti, G
Taxanes stimulate doxorubicin conversion to its cardiotoxic secondary alcohol metabolite : Studies in human myocardium.
2001-01-01 Minotti, G; Giancristofaro, G.; Menna, P.; Salvatorelli, E.; Licata, S.; Saponiero, A.; Gianni, L.
Altered iron regulatory protein activities in doxorubicin-treated cardiomyocytes : Distinct roles of reactive oxygen species and of the secondary alcohol metabolite doxorubicinol
2001-01-01 Minotti, G; Ronchi, R.; Menna, P.; Cairo, G.
Impairment of myocardial contractility by anticancer anthracyclines: role of secondary alcohol metabolites and evidence of reduced toxicity by a novel disaccharide analogue
2001-01-01 Minotti, G; Parlani, M; Salvatorelli, E; Menna, P; Cipollone, A; Animati, F; Maggi, Ca; Manzini, S
Paclitaxel and docetaxel enhance the metabolism of doxorubicin to toxic species in human myocardium
2001-01-01 Minotti, G; Saponiero, A.; Licata, S.; Menna, P.; Calafiore, A. M.; Teodori, G.; Gianni, L.
Doxorubicin irreversibly inactivates Iron Regulatory Proteins 1 and 2 in cardiomyocytes : Evidence for distinct metabolic pathways and implications for iron-mediated cardiotoxicity of antitumor therapy
2001-01-01 Minotti, G.; Ronchi, R.; Salvatorelli, E.; Menna, P; A, ; Cairo, G.
Doxorubicin-Dependent Reduction of Ferrylmyoglobin and Inhibition of Lipid Peroxidation: Implications for Cardiotoxicity of Anticancer Anthracyclines
2002-01-01 Menna, P.; Salvatorelli, E.; Giampietro, R.; Liberi, G.; Teodori, G.; Calafiore, A. M.; Minotti, G
The novel anthracycline MEN 10755 is less cardiotoxic than doxorubicin or epirubicin due to reduced formation and aconitase-reactivity its secondary alcohol metabolite
2003-01-01 Menna, P; Salvatorelli, Emanuela; R., Giampietro; N., Bertani; G., Graiani; F., Animati; C., Goso; C. A., Maggi; S., Mancini; G., Sacco; Minotti, G.
Ferrylmyoglobin-dependent oxidative degradation of doxorubicin: a novel pathway of anthracycline metabolism and toxicity
2003-01-01 Menna, P.; Salvatorelli, E.; Braghiroli, D.; Giampietro, R.; Cartoni, A.; Animati, F.; Minotti, G
Doxorubicin inhibits ferrylmyoglobin-dependent lipid peroxidation
2003-01-01 Minotti, G; Menna, P; Salvatorelli, E; Giampietro, R
Chronic cardiotoxicity of anticancer anthracyclines in the rat: role of secondary metabolites and reduced toxicity by a novel anthracycline with impaired metabolite formation and reactivity
2003-01-01 Sacco, G.; Giampietro, R.; Salvatorelli, E.; Menna, P; Bertani, N.; Graiani, G.; Animati, F.; Goso, C.; Maggi, C. A.; Mancinis, S.; Minotti, G.
Anthracyclines: molecular advances and pharmacological developments in antitumor activity and cardiotoxicity
2004-01-01 Minotti, G; Menna, P; Salvatorelli, E; Cairo, G; Gianni, L.
Oxidative degradation of cardiotoxic anticancer anthracyclines to phthalic acids. Novel function or ferrylmyoglobin
2004-01-01 Cartoni, Antonella; Menna, Pierantonio; Salvatorelli, Emanuela; Braghiroli, Daniela; Giampietro, Rossella; Animati, Fabio; Urbani, Andrea; Del Boccio, Piero; Minotti, Giorgio
Doxorubicin Cardiotoxicity and the Control of Iron Metabolism: Quinone-Dependent and Independent Mechanisms
2004-01-01 Minotti, G.; Recalcati, S.; Menna, P.; Salvatorelli, E.; Corna, G.; Cairo, G.
Molecular determinants of the reduced cardiotoxicity of epirubicin
2005-01-01 Salvatorelli, E.; Guarnieri, S.; Menna, P; Cascegna, S.; Minotti, G.
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