Health care contribution to the climate crisis. Green operating room and green team

Prospective validation of reflux monitoring by impedance-pH in predicting PPI response in typical GERD

Background: The Lyon Consensus proposed a hierarchical approach to GERD diagnosis based on conven-tional and new impedance-pH metrics, namely acid exposure time (AET), number of reflux episodes, post -reflux swallow-induced peristaltic wave (PSPW) index, and mean nocturnal baseline impedance (MNBI).Aims: To define the value of conventional and new impedance-pH parameters as predictors of response to label-dose PPI in typical GERD.Methods: Consecutive adult patients with typical esophageal sym...

Proximal esophageal impedance baseline increases the yield of impedance-pH monitoring for GERD diagnosis and is associated with heartburn response to PPI

BackgroundImpairment of esophageal mucosal integrity as assessed by low mean nocturnal baseline impedance (MNBI) measured in the distal esophagus increases the diagnostic yield of impedance-pH in patients with inconclusive GERD diagnosis as defined by Lyon criteria. AimTo assess the diagnostic yield of MNBI measurement in the proximal esophagus, and its relationship with PPI response. MethodsExpert review of off-therapy impedance-pH tracings from consecutive patients with heartburn, 80 respon...

Psychological distress in inflammatory bowel disease

IntroductionMental health disorders are common in inflammatory bowel disease (IBD) and affect patients' quality of life, impacting on disease outcomes and health care-related costs.Areas coveredEven if psychological issues in IBD patients are highly burdened in terms of quality of life, psychiatric comorbidities still receive less attention into routine care than the physical symptoms of the disease. The present review provides an overview of recent literature, focusing on the association bet...