Magnesium-based bio-absorbable implants (MgBIs) are emerging as a promising alternative to conventional implants in current clinical practice. In this context, surgical planning and management could be significantly enhanced through advanced multiscale and multiphysics numerical models. As a first step in this direction, a phase-field approach is herein presented to model the degradation kinetics of MgBIs. The governing equations are consistently derived by minimizing the free energy, and are numerically solved using a finite-element formulation implemented with in-house codes. The model has been successfully validated by reproducing the dissolution of a cylindrical electrode in an electrolyte solution, and then applied to simulate the degradation of a magnesium-based screw. Available analytical results and experimental observations are well reproduced, highlighting the model’s soundness and effectiveness.

Modeling the Degradation of Bio-absorbable Bone Implants: A Computational Approach

Zoboli L.;Gizzi A.;
2025-01-01

Abstract

Magnesium-based bio-absorbable implants (MgBIs) are emerging as a promising alternative to conventional implants in current clinical practice. In this context, surgical planning and management could be significantly enhanced through advanced multiscale and multiphysics numerical models. As a first step in this direction, a phase-field approach is herein presented to model the degradation kinetics of MgBIs. The governing equations are consistently derived by minimizing the free energy, and are numerically solved using a finite-element formulation implemented with in-house codes. The model has been successfully validated by reproducing the dissolution of a cylindrical electrode in an electrolyte solution, and then applied to simulate the degradation of a magnesium-based screw. Available analytical results and experimental observations are well reproduced, highlighting the model’s soundness and effectiveness.
2025
9783031843785
9783031843792
Bio-absorbable bone implants
Magnesium alloys degradation
Moving boundary problems
Phase-field approach
File in questo prodotto:
Non ci sono file associati a questo prodotto.

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/20.500.12610/96643
Citazioni
  • ???jsp.display-item.citation.pmc??? ND
  • Scopus 5
  • ???jsp.display-item.citation.isi??? ND
social impact