Eighty one patients with breast cancel stages I, II and III (T3a) were given adjuvant treatment with tamoxifen (Nolvadex), chemotherapy, ol both. Most patients had had estrogen and progesterone receptors measurement, Twenty one (63.6%) patients of the tamoxifen group were node positive, all 25 (100%) of the chemotherapy plus tamoxifen group and 13 (56.5%) of the chemotherapy alone group. Tamoxifen was administered for at least 3 years. Disease fi ee survival and overall survival were substantially survival after. treatment with tamoxifen ol chemotherapy pills tamoxifen. Side effects were more numerous nr rd severe in the patients given chemotherapy. In receptor positive elderly breast cancer patients tamoxifen represents an excellent adjuvant therapy independently of disease stage. Chemotherapy should be reserved for subjects at high risk of recurrence in controled clinical trials.
Adjuvant treatment for breast cancer in the elderly
Santini D;
1996-01-01
Abstract
Eighty one patients with breast cancel stages I, II and III (T3a) were given adjuvant treatment with tamoxifen (Nolvadex), chemotherapy, ol both. Most patients had had estrogen and progesterone receptors measurement, Twenty one (63.6%) patients of the tamoxifen group were node positive, all 25 (100%) of the chemotherapy plus tamoxifen group and 13 (56.5%) of the chemotherapy alone group. Tamoxifen was administered for at least 3 years. Disease fi ee survival and overall survival were substantially survival after. treatment with tamoxifen ol chemotherapy pills tamoxifen. Side effects were more numerous nr rd severe in the patients given chemotherapy. In receptor positive elderly breast cancer patients tamoxifen represents an excellent adjuvant therapy independently of disease stage. Chemotherapy should be reserved for subjects at high risk of recurrence in controled clinical trials.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
