Electrospun scaffolds for bone tissue engineering

Tissue engineering aims to regenerate native tissues and will represent the alternative choice of standard surgery for different kind of tissue damages. The funda- mental basis of tissue engineering is the appropriate selection of scaffolds and their morphological, mechanical, chemical, and biomimetic properties, closely related to cell lines that will be seeded therein. The aim of this review is to summarize and report the innovative scientific contri- butions published in the field of orthopedic tissue engi- neering, in particular about bone tissue engineering. We have focused our attention on the electrospinning tech- nique, as a scaffold fabrication method. Electrospun materials are being evaluated as scaffolds for bone tissue engineering, and the results of all these studies clearly indicate that they represent suitable potential substrates for cell-based technologies.