The appearance of emerging variants of SARS-CoV-2 carrying mutations into the spike protein has recently raised concern with respect to tracking their transmission and mitigating the impact in the evolving pandemic across countries. AY.4.2, a recently detected Delta variant sublineage, is considered a new variant under investigation (VUI) as it carries specific genetic signatures present in the spike protein, called Y145H and A222V. Here, using genomic epidemiology, we provide the first preliminary insight regarding the circulation of this emerging VUI in Italy.

SARS-CoV-2 AY.4.2 variant circulating in Italy: Genomic preliminary insight

Angeletti S.;Fogolari M.;De Florio L.;Lintas C.;Spoto S.;Riva E.;Ciccozzi M.
2022-01-01

Abstract

The appearance of emerging variants of SARS-CoV-2 carrying mutations into the spike protein has recently raised concern with respect to tracking their transmission and mitigating the impact in the evolving pandemic across countries. AY.4.2, a recently detected Delta variant sublineage, is considered a new variant under investigation (VUI) as it carries specific genetic signatures present in the spike protein, called Y145H and A222V. Here, using genomic epidemiology, we provide the first preliminary insight regarding the circulation of this emerging VUI in Italy.
2022
Adolescent; Adult; Aged; Child; COVID-19; Female; Genome, Viral; Genomics; Humans; Italy; Male; Middle Aged; Molecular Epidemiology; Mutation; Phylogeny; RNA, Viral; SARS-CoV-2; Young Adult
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/20.500.12610/64412
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