In human validation of the control of a cybernetic sensorized multi degree of freedom hand prosthesis through longitudinally-implanted peripheral-nerves intraneural multielectrode. CyberHand project pretends to develop a cybernetic hand prosthesis able to be controlled with a low cognitive load, directly through the delivering of neural signals and to furnish to the user sensorial information. Final aim is to implement a human hand-like prosthesis that can be embodied in the user body scheme. This project reached the fundamental phase of first clinical validation, called LIFEHAND, during the PhD course. A volunteer subject received the implant of intraneural electrodes into his severed upper limb nerves and has been trained for controlling several types of grip made by the prosthesis. Afferent stimulation and efferent control were investigated through various modalities. Cortical plasticity in the user has been subject of further evaluations. In the following are collected my primary contributes to the experimentation. Specific Objectives a. Specific clinical protocol definition taking into account all the needs coming from physicians and bioengineers. b. Stimulation protocol definition. c. Stimulation/recording system (SRS) settings and integration. d. Electrodes-SRS wiring and shielding . e. Neuroplastic changes evaluation and functional analysis. Requirements, specifications and designing of innovative bidirectional neural interfaces. Starting from the experience achieved with the LIFEHAND experimentation the follow research activities should lead to new insights toward the development of a new generation of intraneural interfaces respecting: a. The possible implications of neuroplastic changes in neural interface user. b. Mechanical tissue-electrode mismatch. c. Foreign Body Reaction against implanted electrodes.

Bidirectional peripheral-nerves interfaces for hand prosthesis control. In human validation and analysis of the induced neuroplasticity and of the foreign body reaction / Giovanni Di Pino - : . , 2010 Apr 16. ((22. ciclo

Bidirectional peripheral-nerves interfaces for hand prosthesis control. In human validation and analysis of the induced neuroplasticity and of the foreign body reaction

DI PINO, GIOVANNI
2010-04-16

Abstract

In human validation of the control of a cybernetic sensorized multi degree of freedom hand prosthesis through longitudinally-implanted peripheral-nerves intraneural multielectrode. CyberHand project pretends to develop a cybernetic hand prosthesis able to be controlled with a low cognitive load, directly through the delivering of neural signals and to furnish to the user sensorial information. Final aim is to implement a human hand-like prosthesis that can be embodied in the user body scheme. This project reached the fundamental phase of first clinical validation, called LIFEHAND, during the PhD course. A volunteer subject received the implant of intraneural electrodes into his severed upper limb nerves and has been trained for controlling several types of grip made by the prosthesis. Afferent stimulation and efferent control were investigated through various modalities. Cortical plasticity in the user has been subject of further evaluations. In the following are collected my primary contributes to the experimentation. Specific Objectives a. Specific clinical protocol definition taking into account all the needs coming from physicians and bioengineers. b. Stimulation protocol definition. c. Stimulation/recording system (SRS) settings and integration. d. Electrodes-SRS wiring and shielding . e. Neuroplastic changes evaluation and functional analysis. Requirements, specifications and designing of innovative bidirectional neural interfaces. Starting from the experience achieved with the LIFEHAND experimentation the follow research activities should lead to new insights toward the development of a new generation of intraneural interfaces respecting: a. The possible implications of neuroplastic changes in neural interface user. b. Mechanical tissue-electrode mismatch. c. Foreign Body Reaction against implanted electrodes.
Neural interface for hand prosthesis
Bidirectional peripheral-nerves interfaces for hand prosthesis control. In human validation and analysis of the induced neuroplasticity and of the foreign body reaction / Giovanni Di Pino - : . , 2010 Apr 16. ((22. ciclo
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/20.500.12610/68264
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