Cardiac allograft vasculopathy (CAV) is the major cause limiting long term graft survival after heart transplantation (HT), and is characterized by changes in coronary artery geometry, such as intimal thickening and vessel remodeling. Given the limited strategies available to reduce its impact on outcome, early diagnosis of CA V -for which intravascular ultrasound (IVUS) is the gold standard - is crucial to appropriately modulate therapy and to reduce contributing risk factors.However, a highly reproducible image-analysis method is required to capture the complex mechanisms beyond CA V-related changes in coronary geometry.
Reproducibility of IVUS Measurements in Heart Transplant Recipients: Increased Quality of Data by Using Dedicated Software for Image Analysis
Grigioni, F;
2008-01-01
Abstract
Cardiac allograft vasculopathy (CAV) is the major cause limiting long term graft survival after heart transplantation (HT), and is characterized by changes in coronary artery geometry, such as intimal thickening and vessel remodeling. Given the limited strategies available to reduce its impact on outcome, early diagnosis of CA V -for which intravascular ultrasound (IVUS) is the gold standard - is crucial to appropriately modulate therapy and to reduce contributing risk factors.However, a highly reproducible image-analysis method is required to capture the complex mechanisms beyond CA V-related changes in coronary geometry.File in questo prodotto:
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