A new thermoelectric ECG model: influence of bundle branch block and variations in body temperature

This work proposes a thermoelectric model to investigate the behavior of specific pathological situation, such as bundle branch block. Impact of temperature is evaluated and its role in controlling the pathology determined. Our proposed 2D thermoelectric model incorporates the heart, lungs, torso, and blood cavities. The Fitzhugh-Nagumo equations that simulate the electrical activity of cardiac myocytes are coupled with temperature equations while considering the parameters of the bundle branch block to analyze their impact on the electrocardiogram. We establish that the presence of bundle branch block significantly affects electrocardiogram morphology, resulting in changes in wave amplitude and interval durations. Moreover, our findings reveal that variations in body temperature alter this pathological condition leading to further distortions in the electrocardiogram. Our thermoelectric model provides valuable insights into the behavior of bundle branch block under temperature variations. This knowledge may potentially contribute to the development of novel treatment and management strategies utilizing thermal control to enhance outcomes for patients presenting similar symptoms.