The plant polyphenol trans-resveratrol (3, 5, 4′-trihydroxystilbene) mainly found in grape, peanut and other few plants, displays a wide range of biological effects.Numerous in vitro studies have described various biological effects of resveratrol. In order to provide more information regarding absorption, metabolism, and bioavailability of resveratrol, various research approaches have been performed, including in vitro, ex vivo, and in vivo models. Inrecent years, the induction of resveratrol synthesis in plants which normally do not accumulate such polyphenol, has been successfully achieved by molecular engineering. Inthis context, the ectopic production of resveratrol has been reported to have positive effects both on plant resistance to biotic stress and the enhancement of the nutritional value of several widely consumed fruits and vegetables. The metabolic engineering of plants offers the opportunity to changethe content of specific phytonutrients in plant - derived foods. This review focuses on the latest findings regardingon resveratrol bioproduction and its effects on the prevention of the major pathological conditions in man.
Resveratrol Biosynthesis: Plant Metabolic Engineering for Nutritional Improvement of Food
De Gara L;
2012-01-01
Abstract
The plant polyphenol trans-resveratrol (3, 5, 4′-trihydroxystilbene) mainly found in grape, peanut and other few plants, displays a wide range of biological effects.Numerous in vitro studies have described various biological effects of resveratrol. In order to provide more information regarding absorption, metabolism, and bioavailability of resveratrol, various research approaches have been performed, including in vitro, ex vivo, and in vivo models. Inrecent years, the induction of resveratrol synthesis in plants which normally do not accumulate such polyphenol, has been successfully achieved by molecular engineering. Inthis context, the ectopic production of resveratrol has been reported to have positive effects both on plant resistance to biotic stress and the enhancement of the nutritional value of several widely consumed fruits and vegetables. The metabolic engineering of plants offers the opportunity to changethe content of specific phytonutrients in plant - derived foods. This review focuses on the latest findings regardingon resveratrol bioproduction and its effects on the prevention of the major pathological conditions in man.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
