Dialysis and adsorption units are commonly used in liver support devices for the removal of albumin-bound toxins, such as bilirubin, and water-soluble low-molecular-weight toxins, such as creatinine. In this paper, the consolidated approach of chemical engineers' to process design is applied to the analysis of the performance of a MARS treatment. The theoretical analysis of the detoxification process is used to discuss some clinical data obtained during a MARS treatment session, referring to bilirubin and creatinine concentration in plasma and different parts of the device circuit.
Molecular Adsorbent Recirculating System (MARS): a Chemical Engineering Analysis of In Vivo Experimental Data
PIEMONTE, Vincenzo;
2009-01-01
Abstract
Dialysis and adsorption units are commonly used in liver support devices for the removal of albumin-bound toxins, such as bilirubin, and water-soluble low-molecular-weight toxins, such as creatinine. In this paper, the consolidated approach of chemical engineers' to process design is applied to the analysis of the performance of a MARS treatment. The theoretical analysis of the detoxification process is used to discuss some clinical data obtained during a MARS treatment session, referring to bilirubin and creatinine concentration in plasma and different parts of the device circuit.File in questo prodotto:
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