IRIS
SALVATORELLI, EMANUELA
 Distribuzione geografica
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Continente #
AS - Asia 3.863
NA - Nord America 700
EU - Europa 318
SA - Sud America 99
AF - Africa 19
OC - Oceania 12
Totale 5.011
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Nazione #
SG - Singapore 2.987
US - Stati Uniti d'America 656
CN - Cina 450
HK - Hong Kong 297
GB - Regno Unito 88
BR - Brasile 76
DE - Germania 67
VN - Vietnam 48
IT - Italia 44
CZ - Repubblica Ceca 34
CA - Canada 19
IN - India 19
FI - Finlandia 16
MX - Messico 15
NL - Olanda 15
ID - Indonesia 12
AU - Australia 11
JP - Giappone 10
ZA - Sudafrica 9
FR - Francia 8
PL - Polonia 8
AR - Argentina 7
BD - Bangladesh 7
UA - Ucraina 7
BE - Belgio 6
PK - Pakistan 6
TR - Turchia 6
CO - Colombia 4
PT - Portogallo 4
PY - Paraguay 4
TW - Taiwan 4
AL - Albania 3
CL - Cile 3
CR - Costa Rica 3
DO - Repubblica Dominicana 3
LT - Lituania 3
SE - Svezia 3
AE - Emirati Arabi Uniti 2
AT - Austria 2
EC - Ecuador 2
EE - Estonia 2
ES - Italia 2
GE - Georgia 2
IE - Irlanda 2
MY - Malesia 2
NP - Nepal 2
TN - Tunisia 2
UZ - Uzbekistan 2
AO - Angola 1
BG - Bulgaria 1
BO - Bolivia 1
BY - Bielorussia 1
CV - Capo Verde 1
DK - Danimarca 1
DM - Dominica 1
EG - Egitto 1
GA - Gabon 1
IQ - Iraq 1
JO - Giordania 1
KN - Saint Kitts e Nevis 1
KZ - Kazakistan 1
LK - Sri Lanka 1
MR - Mauritania 1
NG - Nigeria 1
NZ - Nuova Zelanda 1
PA - Panama 1
PE - Perù 1
PH - Filippine 1
RO - Romania 1
SA - Arabia Saudita 1
SN - Senegal 1
SO - Somalia 1
TT - Trinidad e Tobago 1
VE - Venezuela 1
YE - Yemen 1
Totale 5.011
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Città #
Hong Kong 295
Singapore 274
Ashburn 173
Hefei 161
Beijing 93
Boardman 93
London 72
Dallas 62
Shanghai 52
Munich 38
Los Angeles 29
Rome 27
Council Bluffs 26
Brno 23
San Francisco 23
Redmond 21
Ho Chi Minh City 16
Amsterdam 14
Pune 13
Mexico City 12
Seattle 12
São Paulo 12
Guangzhou 11
Hanoi 11
Santa Clara 11
New York 10
Olomouc 10
Turku 10
Tokyo 9
Toronto 9
Boston 8
Washington 8
Brooklyn 7
Haiphong 7
Manchester 7
Helsinki 6
Warsaw 6
Chicago 5
Melbourne 5
Atlanta 4
Biên Hòa 4
Campinas 4
San Jose 4
Shenzhen 4
Ankara 3
Canberra 3
Dhaka 3
Haikou 3
Hangzhou 3
Johannesburg 3
Karachi 3
Mol 3
Montreal 3
Paris 3
Rio de Janeiro 3
San José 3
Stockholm 3
Sydney 3
Taipei 3
The Dalles 3
Tirana 3
Wuhan 3
Asunción 2
Augusta 2
Aversa 2
Chennai 2
Colombo 2
Concord 2
Dublin 2
Florence 2
Genoa 2
Hanover 2
Hasselt 2
Iowa City 2
Kuala Lumpur 2
Limeira 2
Lodz 2
Luoyang 2
Medellín 2
New Delhi 2
North Liberty 2
Nuremberg 2
Oklahoma City 2
Palermo 2
Phoenix 2
Porto 2
Quito 2
Tallinn 2
Tashkent 2
Tbilisi 2
Thái Nguyên 2
Topeka 2
Vilnius 2
West Jordan 2
Xiamen 2
Zhengzhou 2
Alcobaça 1
Alfenas 1
Almaty 1
Amman 1
Totale 1.827
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Nome #
Cardiovascular safety of anti-TNF-alpha therapies: Facts and unsettled issues. 208
Anthracyclines and Cardiotoxicity: Is CARP a Forgotten Biomarker? 190
Choosing Antifungals for the Midostaurin-Treated Patient: Does CYP3A4 Outweigh Recommendations? A Brief Insight from Real Life 188
Minimal sampling colistin pharmacokinetics in critically ill patients 187
Cancer drugs and QT prolongation: weighing risk against benefit 186
Doxorubicinolone formation and efflux : A salvage pathway against epirubicin accumulation in human heart 184
The endogenous lusitropic and chronotropic agent, B-type natriuretic peptide, limits cardiac troponin release in cancer patients with an early impairment of myocardial relaxation induced by anthracyclines 176
Cardiovascular toxicity of antitumor drugs :Translating molecular mechanisms into clinical facts 173
Pharmacology of Ranolazine versus Common Cardiovascular Drugs in Patients with Early Diastolic Dysfunction Induced by Anthracyclines or Nonanthracycline Chemotherapeutics: A Phase 2b Minitrial 171
Defective taxane stimulation of epirubicinol formation in the human heart: Insights into the cardiac tolerability of epirubicin-taxane chemotherapies 163
Anthracycline cardiotoxicity in breast cancer patients: Synergism with trastuzumab and taxanes 160
4’- Epidoxorubicin to reexplore anthracycline degradation in cardiomyocytes 159
Chronic cardiotoxicity of anticancer anthracyclines in the rat: role of secondary metabolites and reduced toxicity by a novel anthracycline with impaired metabolite formation and reactivity 142
Beyond hypertension: Diastolic dysfunction associated with cancer treatment in the era of cardio-oncology 127
Anthracyclines 112
Pharmacology of cardio-oncology: chronotropic and lusitropic effects of B-type natriuretic peptide in cancer patients with early diastolic dysfunction induced by anthracycline or nonanthracycline chemotherapy 109
Anthracycline Cardiotoxicity 108
Anthracycline degradation in cardiomyocytes: a journey to oxidative survival 100
Anthracycline Cardiotoxicity 92
Defective one or two electron reduction of the anticancer anthracycline epirubicin in human heart: Relative importance of vesicular sequestration and impaired efficiency of electron addition 88
Cardiotoxicity of antitumor drugs 76
CARDIAC ANTHRACYCLINE ACCUMULATION AND B-TYPE NATRIURETIC PEPTIDE TO DEFINE RISK AND PREDICTORS OF CANCER TREATMENT RELATED EARLY DIASTOLIC DYSFUNCTION 72
Low dose anthracycline and risk of heart failure in a pharmacokinetic model of human myocardium exposure: analog specificity and role of secondary alcohol metabolites 72
Cardiotoxicity of targeted cancer drugs: concerns, “The cart before the horse,” and lessons from trastuzumab 71
Advances in Bruton tyrosine kinase (Btk) inhibition are steered by Bruton tyrosine kinase phylogeny 56
Anthracyclines, diastolic dysfunction and the road to heart failure in Cancer survivors: An untold story 55
Anthracyclines: molecular advances and pharmacological developments in antitumor activity and cardiotoxicity 55
Rethinking drugs from chemistry to therapeutic opportunities: Pixantrone beyond Anthracyclines. 48
Pharmacology of Cardio-Oncology 48
What is cardiotoxicity? 46
Pharmacokinetic characterization of amrubicin cardiac safety in an ex vivo human myocardial strip model II. Amrubicin shows metabolic advantages over doxorubicin and epirubicin 44
From Cardiac Anthracycline Accumulation to Real-Life Risk for Early Diastolic Dysfunction: A Translational Approach 43
Paclitaxel and docetaxel stimulation of doxorubicinol formation in the human heart: Implications for cardiotoxicity of doxorubicin-taxane chemotherapies 40
Doxorubicin-Dependent Reduction of Ferrylmyoglobin and Inhibition of Lipid Peroxidation: Implications for Cardiotoxicity of Anticancer Anthracyclines 39
Further analytical, pharmacokinetic, and clinical observations on low-dose ponatinib in patients with Philadelphia chromosome-positive acute lymphoblastic leukemia 39
Predictors of early or delayed diastolic dysfunction after anthracycline-based or nonanthracycline chemotherapy: a pharmacological appraisal 38
Isavuconazole: case report and pharmacokinetic considerations 37
Modeling human myocardium exposure to doxorubicin defines the risk of heart failure from low-dose doxorubicin 37
Ponatinib induces a persistent molecular response and graft-versus-host disease/graft-versus-leukemia effect in a patient with Philadelphia-positive acute lymphoblastic leukemia with a T315I mutation following early relapse after allogeneic transplant 37
Doxorubicin irreversibly inactivates Iron Regulatory Proteins 1 and 2 in cardiomyocytes : Evidence for distinct metabolic pathways and implications for iron-mediated cardiotoxicity of antitumor therapy 37
NEW TARGETED DRUGS FOR ACUTE MYELOID LEUKEMIA AND ANTIFUNGALS: PHARMACOKINETIC CHALLENGES AND OPPORTUNITIES 36
Mechanisms and clinical course of cardiovascular toxicity of cancer treatment II. Hematology 36
Pharmacokinetics of pegylated liposomal doxorubicin administered by intraoperative hyperthermic intraperitoneal chemotherapy to patients with advanced ovarian cancer and peritoneal carcinomatosis 36
Low level tumor necrosis factor-alpha protects cardiomyocytes against high level tumor necrosis factor-alpha: brief insight into a beneficial paradox 35
Oxidative degradation of cardiotoxic anticancer anthracyclines to phthalic acids. Novel function or ferrylmyoglobin 34
The novel anthracenedione, pixantrone, lacks redox activity and inhibits doxorubicinol formation in human myocardium: Insight to explain the cardiac safety of pixantrone in doxorubicin treated patients 32
Matters of the heart: The case of TNF-alpha targeting drugs 32
The concomitant management of cancer therapy and cardiac therapy 31
Telaprevir raises the plasma/whole blood ribavirin ratio: trying to come full circle on a dangerous relationship 30
Pharmacological Foundation of Cardio-Oncology 29
Formation of toxic anthracycline secondary alcohol metabolites in human myocardium: Comparisons between doxorubicin and epirubicin and effects of paclitaxel, docetaxel, and the epothilones BMS310705 and BMS247550 29
Doxorubicin metabolism to toxic species in human myocardium: stimulation by paclitaxel and docetaxel but not BMS 184476 or BMS 188797 29
Doxorubicin degradation in cardiomyocytes 28
Pharmacokinetic characterization of amrubicin cardiac safety in an ex vivo human myocardial strip model I Amrubicin accumulates to a lower level than doxorubicin or epirubicin 28
Managing anthracycline-induced cardiotoxicity: beginning with the end in mind 28
Modified colistin regimen for critically ill patients with acute renal impairment and continuous renal replacement therapy 28
Molecular determinants of the reduced cardiotoxicity of epirubicin 28
Posaconazole and midostaurin in patients with FLT3-mutated acute myeloid leukemia: Pharmacokinetic interactions and clinical facts in a real life study 27
Tumour necrosis factor alpha (TNFα)cardiomyocyte preconditioning: clues to explain anti-TNFα agents contraindication in severe heart failure 27
In vitro modelling of the structure-activity determinants of anthracycline cardiotoxicity. 26
Tnf-alpha induced cardioprotection: effects on reactive oxygen species (ros) and apoptosis 26
Impairment of myocardial contractility by anticancer anthracyclines: role of secondary alcohol metabolites and evidence of reduced toxicity by a novel disaccharide analogue 25
Ferrylmyoglobin-dependent oxidative degradation of doxorubicin: a novel pathway of anthracycline metabolism and toxicity 25
Phase IB and pharmacological study of the novel taxane BMS-184476 in combination with doxorubicin 25
Efficacy and safety of low dose ponatinib in a case of Ph-positive acute lymphoblastic leukaemia 24
The use of pegylated liposomal doxorubicin with hyperthermic intraperitoneal chemotherapy (HIPEC) in patients undergoing cytoreductive surgery (CS) for peritoneal carcinomatosis of ovarian origin 24
Doxorubicin dependent reduction of hypervalent ferrylmyoglobin: One more evidence against the oxidative nature of doxorubicin-induced cardiotoxicity 24
Primary prevention strategies for anthracycline cardiotoxicity: a brief overview 23
Role of secondary alcohol metabolites in anthracycline cardiotoxicity: from hypotheses to new drugs 23
Translating molecular mechanisms into clinical facts 23
Increasing doxorubicin antitumor activity through COX-2 inhibition without increasing cardiotoxicity 23
Taxanes stimolate Doxorubicin conversion to its cardiotoxic secondary alcohol metabolite doxorubicinol: studies in human myocardium 23
Taxanes stimulate doxorubicin conversion to its cardiotoxic secondary alcohol metabolite : Studies in human myocardium. 23
Tumor necrosis factor alpha and cardiomyocytes: evidence for a self-protective preconditioning 22
Doxorubicin inhibits ferrylmyoglobin-dependent lipid peroxidation 22
Humans and Rodents: The Case of hOAT4 and mOat5 21
Do you know pixantrone? 20
Pixantrone (PIX) Inhibition of Doxorubicinol (DOXOL) Formation in Human Myocardium: Implications for Cardiac Safety in Non-Hodgkin Lymphoma (NHL) Patients with Prior Anthracycline Treatment 19
The novel anthracycline MEN 10755 is less cardiotoxic than doxorubicin or epirubicin due to reduced formation and aconitase-reactivity its secondary alcohol metabolite 19
The reality of pixantrone in real life 17
Doxorubicin Cardiotoxicity and the Control of Iron Metabolism: Quinone-Dependent and Independent Mechanisms 17
Totale 5.090
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Categoria #
all - tutte 38.810
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 38.810
Salva come PNG Salva come JPEG


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/2022186 0 4 0 0 0 0 1 73 3 0 4 101
2022/202346 1 1 1 3 2 2 10 0 2 3 20 1
2023/2024280 5 32 8 12 32 123 4 16 2 7 4 35
2024/20253.593 74 34 107 13 42 68 37 20 222 238 1.303 1.435
2025/2026985 294 186 127 209 108 61 0 0 0 0 0 0
Totale 5.090