IRIS
MENNA, PIERANTONIO
 Distribuzione geografica
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Continente #
AS - Asia 4.967
NA - Nord America 2.097
EU - Europa 812
SA - Sud America 213
Continente sconosciuto - Info sul continente non disponibili 110
AF - Africa 33
OC - Oceania 13
Totale 8.245
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Nazione #
SG - Singapore 3.605
US - Stati Uniti d'America 1.972
CN - Cina 682
HK - Hong Kong 371
IT - Italia 324
BR - Brasile 130
GB - Regno Unito 119
FR - Francia 94
DE - Germania 91
VN - Vietnam 66
BD - Bangladesh 56
CZ - Repubblica Ceca 54
CA - Canada 52
IN - India 44
MX - Messico 44
FI - Finlandia 26
NL - Olanda 22
AR - Argentina 20
CO - Colombia 20
ID - Indonesia 18
PH - Filippine 18
EC - Ecuador 13
ZA - Sudafrica 13
AU - Australia 12
MY - Malesia 12
PL - Polonia 11
TR - Turchia 11
VE - Venezuela 11
ES - Italia 10
SA - Arabia Saudita 10
UA - Ucraina 10
JP - Giappone 9
PK - Pakistan 9
PY - Paraguay 8
CL - Cile 7
CR - Costa Rica 7
RU - Federazione Russa 7
TW - Taiwan 7
BE - Belgio 6
IQ - Iraq 6
JM - Giamaica 6
JO - Giordania 6
MD - Moldavia 6
AE - Emirati Arabi Uniti 5
NP - Nepal 5
PT - Portogallo 5
AL - Albania 4
EE - Estonia 4
GT - Guatemala 4
UZ - Uzbekistan 4
AT - Austria 3
GE - Georgia 3
IE - Irlanda 3
KR - Corea 3
LT - Lituania 3
SE - Svezia 3
TH - Thailandia 3
TN - Tunisia 3
AO - Angola 2
BO - Bolivia 2
CI - Costa d'Avorio 2
DO - Repubblica Dominicana 2
EG - Egitto 2
HN - Honduras 2
IL - Israele 2
MA - Marocco 2
MM - Myanmar 2
NI - Nicaragua 2
PE - Perù 2
SV - El Salvador 2
BA - Bosnia-Erzegovina 1
BF - Burkina Faso 1
BG - Bulgaria 1
BH - Bahrain 1
BN - Brunei Darussalam 1
BY - Bielorussia 1
CV - Capo Verde 1
DK - Danimarca 1
DM - Dominica 1
ET - Etiopia 1
GA - Gabon 1
KG - Kirghizistan 1
KH - Cambogia 1
KN - Saint Kitts e Nevis 1
KZ - Kazakistan 1
LB - Libano 1
LK - Sri Lanka 1
LV - Lettonia 1
LY - Libia 1
ME - Montenegro 1
MR - Mauritania 1
NG - Nigeria 1
NZ - Nuova Zelanda 1
OM - Oman 1
PA - Panama 1
RO - Romania 1
RW - Ruanda 1
SN - Senegal 1
SY - Repubblica araba siriana 1
TT - Trinidad e Tobago 1
Totale 8.134
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Città #
San Jose 562
Singapore 409
Hong Kong 369
Ashburn 318
Rome 231
Beijing 210
Hefei 184
Council Bluffs 131
Boardman 106
Columbus 100
London 83
Lauterbourg 79
Dallas 68
Santa Clara 63
Shanghai 61
Munich 48
Los Angeles 40
Brno 35
Mexico City 26
New York 26
San Francisco 26
Ho Chi Minh City 22
Pune 20
Redmond 20
Amsterdam 18
São Paulo 18
Olomouc 17
Phoenix 16
Hanoi 15
Turku 14
Seattle 13
Washington 13
Guangzhou 12
Toronto 12
Helsinki 11
Manchester 11
Boston 9
Brooklyn 9
Bogotá 8
Chicago 8
Montreal 8
Nuremberg 8
Orem 8
Tokyo 8
Warsaw 8
Rio de Janeiro 7
San José 7
Brasília 6
Buffalo 6
Caracas 6
Kuala Lumpur 6
Melbourne 6
Milan 6
Amman 5
Campinas 5
Chennai 5
Frankfurt am Main 5
Guayaquil 5
Haiphong 5
Hangzhou 5
Johannesburg 5
Las Vegas 5
Palermo 5
Philadelphia 5
Riyadh 5
Ankara 4
Atlanta 4
Biên Hòa 4
Charlotte 4
Dhaka 4
Haikou 4
Manila 4
Naples 4
Paris 4
Piscataway 4
Taipei 4
Tashkent 4
The Dalles 4
Tirana 4
Wuhan 4
Alessandria 3
Buenos Aires 3
Canberra 3
Colombo 3
Columbia 3
Dublin 3
Genoa 3
Guatemala City 3
Hanover 3
Hyderabad 3
Istanbul 3
Jakarta 3
Karachi 3
Lancaster 3
Memphis 3
Miami 3
Mol 3
New Delhi 3
Newark 3
Oklahoma City 3
Totale 3.711
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Nome #
Pharmacology of Ranolazine versus Common Cardiovascular Drugs in Patients with Early Diastolic Dysfunction Induced by Anthracyclines or Nonanthracycline Chemotherapeutics: A Phase 2b Minitrial 241
Cardiovascular safety of anti-TNF-alpha therapies: Facts and unsettled issues. 234
Doxorubicinolone formation and efflux : A salvage pathway against epirubicin accumulation in human heart 215
Choosing Antifungals for the Midostaurin-Treated Patient: Does CYP3A4 Outweigh Recommendations? A Brief Insight from Real Life 211
Altered iron regulatory protein activities in doxorubicin-treated cardiomyocytes : Distinct roles of reactive oxygen species and of the secondary alcohol metabolite doxorubicinol 210
Anthracyclines and Cardiotoxicity: Is CARP a Forgotten Biomarker? 209
Cancer drugs and QT prolongation: weighing risk against benefit 208
Minimal sampling colistin pharmacokinetics in critically ill patients 204
The endogenous lusitropic and chronotropic agent, B-type natriuretic peptide, limits cardiac troponin release in cancer patients with an early impairment of myocardial relaxation induced by anthracyclines 201
4’- Epidoxorubicin to reexplore anthracycline degradation in cardiomyocytes 199
Cardiovascular toxicity of antitumor drugs :Translating molecular mechanisms into clinical facts 199
Beyond hypertension: Diastolic dysfunction associated with cancer treatment in the era of cardio-oncology 197
Cardio-oncology in clinical studies and real life 189
Defective taxane stimulation of epirubicinol formation in the human heart: Insights into the cardiac tolerability of epirubicin-taxane chemotherapies 182
Chronic cardiotoxicity of anticancer anthracyclines in the rat: role of secondary metabolites and reduced toxicity by a novel anthracycline with impaired metabolite formation and reactivity 165
Anthracycline Cardiotoxicity 151
Pharmacology of cardio-oncology: chronotropic and lusitropic effects of B-type natriuretic peptide in cancer patients with early diastolic dysfunction induced by anthracycline or nonanthracycline chemotherapy 141
Anthracyclines 131
Anthracycline degradation in cardiomyocytes: a journey to oxidative survival 130
Early Diastolic Dysfunction after Cancer Chemotherapy: Primary Endpoint Results of a Multicenter Cardio-Oncology Study 128
Anthracycline metabolism and toxicity in human myocardyum: Comparisons between doxorubicin, epirubicin, and a novel disaccaride analogue with redeced formation and [4Fe-4S]-reactivity of its secondary alchol metabolite 128
Anthracycline Cardiotoxicity 116
Defective one or two electron reduction of the anticancer anthracycline epirubicin in human heart: Relative importance of vesicular sequestration and impaired efficiency of electron addition 110
An introduction to the metabolic determinants of anthracycline cardiotoxicity 108
Cardiotoxicity of antitumor drugs 107
CARDIAC ANTHRACYCLINE ACCUMULATION AND B-TYPE NATRIURETIC PEPTIDE TO DEFINE RISK AND PREDICTORS OF CANCER TREATMENT RELATED EARLY DIASTOLIC DYSFUNCTION 103
Advances in Bruton tyrosine kinase (Btk) inhibition are steered by Bruton tyrosine kinase phylogeny 98
Cardiotoxicity of targeted cancer drugs: concerns, “The cart before the horse,” and lessons from trastuzumab 97
Low dose anthracycline and risk of heart failure in a pharmacokinetic model of human myocardium exposure: analog specificity and role of secondary alcohol metabolites 96
Anthracyclines: molecular advances and pharmacological developments in antitumor activity and cardiotoxicity 94
Anthracyclines, diastolic dysfunction and the road to heart failure in Cancer survivors: An untold story 80
Pharmacokinetic characterization of amrubicin cardiac safety in an ex vivo human myocardial strip model II. Amrubicin shows metabolic advantages over doxorubicin and epirubicin 78
Isavuconazole: case report and pharmacokinetic considerations 77
Rethinking drugs from chemistry to therapeutic opportunities: Pixantrone beyond Anthracyclines. 73
Ibrutinib and Bruton's tyrosine kinase inhibitors in chronic lymphocytic leukemia: focus on atrial fibrillation and ventricular tachyarrhythmias/sudden cardiac death 73
Modeling human myocardium exposure to doxorubicin defines the risk of heart failure from low-dose doxorubicin 72
Telaprevir raises the plasma/whole blood ribavirin ratio: trying to come full circle on a dangerous relationship 72
Low level tumor necrosis factor-alpha protects cardiomyocytes against high level tumor necrosis factor-alpha: brief insight into a beneficial paradox 71
Pharmacology of Cardio-Oncology 68
Development and Validation of a UHPLC-MS/MS-Based Method to Quantify Cenobamate in Human Plasma Samples 67
Safety and tolerability of a novel oral nutritional supplement in healthy volunteers 67
What is cardiotoxicity? 66
Further analytical, pharmacokinetic, and clinical observations on low-dose ponatinib in patients with Philadelphia chromosome-positive acute lymphoblastic leukemia 65
In vitro modelling of the structure-activity determinants of anthracycline cardiotoxicity. 65
From Cardiac Anthracycline Accumulation to Real-Life Risk for Early Diastolic Dysfunction: A Translational Approach 64
Paclitaxel and docetaxel stimulation of doxorubicinol formation in the human heart: Implications for cardiotoxicity of doxorubicin-taxane chemotherapies 64
Predictors of early or delayed diastolic dysfunction after anthracycline-based or nonanthracycline chemotherapy: a pharmacological appraisal 64
Doxorubicin-Dependent Reduction of Ferrylmyoglobin and Inhibition of Lipid Peroxidation: Implications for Cardiotoxicity of Anticancer Anthracyclines 63
NEW TARGETED DRUGS FOR ACUTE MYELOID LEUKEMIA AND ANTIFUNGALS: PHARMACOKINETIC CHALLENGES AND OPPORTUNITIES 62
Pharmacokinetics of pegylated liposomal doxorubicin administered by intraoperative hyperthermic intraperitoneal chemotherapy to patients with advanced ovarian cancer and peritoneal carcinomatosis 62
The concomitant management of cancer therapy and cardiac therapy 61
Posaconazole and midostaurin in patients with FLT3-mutated acute myeloid leukemia: Pharmacokinetic interactions and clinical facts in a real life study 60
Paclitaxel and docetaxel enhance the metabolism of doxorubicin to toxic species in human myocardium 60
The novel anthracenedione, pixantrone, lacks redox activity and inhibits doxorubicinol formation in human myocardium: Insight to explain the cardiac safety of pixantrone in doxorubicin treated patients 59
Pharmacological Foundation of Cardio-Oncology 58
Doxorubicin irreversibly inactivates Iron Regulatory Proteins 1 and 2 in cardiomyocytes : Evidence for distinct metabolic pathways and implications for iron-mediated cardiotoxicity of antitumor therapy 57
Modified colistin regimen for critically ill patients with acute renal impairment and continuous renal replacement therapy 56
Oxidative degradation of cardiotoxic anticancer anthracyclines to phthalic acids. Novel function or ferrylmyoglobin 56
Doxorubicin metabolism to toxic species in human myocardium: stimulation by paclitaxel and docetaxel but not BMS 184476 or BMS 188797 55
Doxorubicin degradation in cardiomyocytes 48
Matters of the heart: The case of TNF-alpha targeting drugs 48
Managing anthracycline-induced cardiotoxicity: beginning with the end in mind 48
MEN 10755 : A novel disaccharide anthracycline with a reduced level of formation and [4Fe-4S]-reactivity of toxic alcohol metabolite in human heart . 48
The novel anthracycline MEN 10755 is less cardiotoxic than doxorubicin or epirubicin due to reduced formation and aconitase-reactivity its secondary alcohol metabolite 48
Impairment of myocardial contractility by anticancer anthracyclines: role of secondary alcohol metabolites and evidence of reduced toxicity by a novel disaccharide analogue 47
Tumour necrosis factor alpha (TNFα)cardiomyocyte preconditioning: clues to explain anti-TNFα agents contraindication in severe heart failure 47
Pharmacokinetic characterization of amrubicin cardiac safety in an ex vivo human myocardial strip model I Amrubicin accumulates to a lower level than doxorubicin or epirubicin 46
Primary prevention strategies for anthracycline cardiotoxicity: a brief overview 46
The use of pegylated liposomal doxorubicin with hyperthermic intraperitoneal chemotherapy (HIPEC) in patients undergoing cytoreductive surgery (CS) for peritoneal carcinomatosis of ovarian origin 46
Quantitative Analysis of Cenobamate and Concomitant Anti-Seizure Medications in Human Plasma via Ultra-High Performance Liquid Chromatography–Tandem Mass Spectrometry 46
The reality of pixantrone in real life 45
Role of secondary alcohol metabolites in anthracycline cardiotoxicity: from hypotheses to new drugs 45
Molecular determinants of the reduced cardiotoxicity of epirubicin 45
Doxorubicin dependent reduction of hypervalent ferrylmyoglobin: One more evidence against the oxidative nature of doxorubicin-induced cardiotoxicity 45
MEN 10755: a novel disaccaride anthracycline with a reduced level of formation and [4Fe-4S]- reactivity of toxic alcohol metabolite in human myocardium 44
Tumor necrosis factor alpha and cardiomyocytes: evidence for a self-protective preconditioning 43
Tnf-alpha induced cardioprotection: effects on reactive oxygen species (ros) and apoptosis 43
High Incidence of Invasive Fungal Diseases in Patients with FLT3-Mutated AML Treated with Midostaurin: Results of a Multicenter Observational SEIFEM Study 43
Translating molecular mechanisms into clinical facts 42
Doxorubicin inhibits ferrylmyoglobin-dependent lipid peroxidation 42
Taxanes stimolate Doxorubicin conversion to its cardiotoxic secondary alcohol metabolite doxorubicinol: studies in human myocardium 42
Ferrylmyoglobin-dependent oxidative degradation of doxorubicin: a novel pathway of anthracycline metabolism and toxicity 42
Recommendations for the harmonization of reference intervals in the therapeutic monitoring of antiepileptic drugs/Indicazioni per l’armonizzazione degli intervalli di riferimento nel monitoraggio terapeutico di farmaci antiepilettici 41
Efficacy and safety of low dose ponatinib in a case of Ph-positive acute lymphoblastic leukaemia 40
Defective one or two electron reduction of the anticancer anthracycline epirubicin in human heart: relative importance of vesicular sequestration and impaired efficiency of electron addition J. Biol. Chem 40
Do you know pixantrone? 39
In ®Entresto we trust 39
Doxorubicin Cardiotoxicity and the Control of Iron Metabolism: Quinone-Dependent and Independent Mechanisms 39
Pixantrone (PIX) Inhibition of Doxorubicinol (DOXOL) Formation in Human Myocardium: Implications for Cardiac Safety in Non-Hodgkin Lymphoma (NHL) Patients with Prior Anthracycline Treatment 38
Taxanes stimulate doxorubicin conversion to its cardiotoxic secondary alcohol metabolite : Studies in human myocardium. 38
Humans and Rodents: The Case of hOAT4 and mOat5 37
Increasing doxorubicin antitumor activity through COX-2 inhibition without increasing cardiotoxicity 37
Cenobamate modulates EEG cortical activity and connectivity in individuals with drug-resistant epilepsy: a pharmaco-EEG study 36
Correction: Infectious complications of targeted drugs and biotherapies in acute leukemia. Clinical practice guidelines by the European Conference on Infections in Leukemia (ECIL), a joint venture of the European Group for Blood and Marrow Transplantation (EBMT), the European Organization for Research and Treatment of Cancer (EORTC), the International Immunocompromised Host Society (ICHS) and the European Leukemia Net (ELN) 32
Adjudication of Adverse Cardiovascular Events in Patients with Chronic Lymphocytic Leukaemia Treated with Ibrutinib: Deaths in GLOW or Blowing in the Wind? 13
Fixed-duration therapy of chronic lymphocytic leukemia with venetoclax and Bruton tyrosine kinase inhibitors: an insight into differences between ibrutinib and acalabrutinib 11
Indications for the harmonization of the therapeutic ranges for antifungal agents 10
Pharmacogenetic testing in Italy: results of a nationwide survey by the Joint Working Group for the pharmacogenetics implementation in Italy 9
Optimizing Treatment, Minimizing Risk: Therapeutic Drug Monitoring in Hematological Malignancies 7
Infectious complications of targeted drugs and biotherapies in acute leukemia. Clinical practice guidelines by the European Conference on Infections in Leukemia (ECIL), a joint venture of the European Group for Blood and Marrow Transplantation (EBMT), the European Organization for Research and Treatment of Cancer (EORTC), the International Immunocompromised Host Society (ICHS) and the European Leukemia Net (ELN) 3
Totale 8.245
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Categoria #
all - tutte 52.589
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 52.589
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/2022214 0 0 0 0 0 0 1 92 4 0 5 112
2022/202356 2 1 1 4 2 2 15 0 3 3 22 1
2023/2024333 6 35 11 15 37 146 1 16 2 8 4 52
2024/20254.043 102 36 123 15 45 77 40 21 250 263 1.446 1.625
2025/20262.976 336 204 131 250 139 94 923 205 219 257 106 112
2026/2027619 74 334 211 0 0 0 0 0 0 0 0 0
Totale 8.245