Towards Non-Invasive Hemodynamic Monitoring: A Feasibility Analysis of Left Ventricular Ejection Time (LVET) Measurement with Wearable Inertial Sensors in Aortic Stenosis Patients

This study aimed to assess the feasibility of measuring Left Ventricular Ejection Time (LVET) using wearable inertial sensors in patients with aortic stenosis (AS) during pretranscatheter aortic valve implantation (pre-TAVI) evaluation. 11 patients with symptomatic AS undergoing pre-TAVI assessment were included. LVET was measured at 5 different locations using inertial sensors: aortic valve (AV), pulmonary valve (PV), transpulmonary valve (TV), mitral valve (MV) and xiphoid process (X). The results were compared with LVET measurements obtained in the same 5 positions from 11 healthy subjects, maintaining identical experimental conditions. It was found that the sensors, as reported in the literature, measure higher LVET values in patients with AS. The dispersion between different positions was calculated for each subject, supporting the validity of the LVET measurement by demonstrating limited variation across sensor placements. This demonstrated the feasibility of using non-invasive sensors for this type of measurement.